News

March 2019: Madhuri presented her work within the department seminar series. Congrats, Madhuri!

March 2019: Shelby joins the Darie Lab!

Shelby is a freshman at Clarkson, majoring in Biomolecular Science. She is a member and the fundraising chair of Tri-Beta, the Biology Honors Society. She is interested in pursuing a future career as a psychiatrist or geneticist. Outside of school, she enjoys swimming, hiking, reading, travel, and participating in equestrian competitions. Welcome to our lab, Shelby!

March 2019: Darie Lab attends the Pittcon Conference in Philadelphia, PA

March 2019: Madhuri presents a poster at the ACS NNY section at SUNY Plattsburgh and wins the best poster awad. Congrats, Madhuri!

January 2019: Dr. Fernando and the Darie Lab, together with Rena, an Engineering grad student

January 2019: Jessica Beverly joins the Darie Lab.

Jess is a senior Biomolecular Science major at Clarkson University. She is heavily involved in Clarkson's Alumni Association. Her love for research stems from a long family history of genetic health issues and a desire to help them. When she is not in class, she is most likely watching Netflix with her roommates or playing with her dog. Jess's plans for after graduation are to get a job and eventually teach at the high school or college level. Welcome to our lab, Jessica!

November 2018: Emma receives the Graduate Student Award at the Eastern Analytical Symposium, Princeton, NJ

November 2018: Members of Darie Lab attend the Eastern Analytical Symposium in Princeton, NJ

November 2018: Members of Darie Lab present their work at the Eastern Analytical Symposium in Princeton, NJ

November 2018: Emma receives some support in presenting her work from her mom, Kelly, the honorific lab member

November 2018: Emma and Devika deliver oral presentations at the Eastern Analytical Symposium in Princeton, NJ

October 2018: Dr. Mesaros is invited by the Proteomics Lab to present a seminar at Clarkson; she delivers two lectures: Walsh seminar series and Chemistry seminar

October 2018: Zach Sechrist joins the Biochemistry & Proteomics Lab

Zach is pursuing a double major in Biomolecular science and Chemistry. He is a member of Clarkson’s colleges against cancer and doctor’s without borders. In his free time, he enjoys hiking and rock climbing. He wishes to pursue a PhD in biochemistry and later work for a pharmaceutical company performing research and development. Welcome to our lab, Zach!

October 2018: Brianna Larose joins the Biochemistry & Proteomics Lab

Brianna is a sophomore Honors student at Clarkson University. She is majoring in Chemical Engineering with minors in Biomedical Engineering and Chemistry. She is interested in pursuing a career in research and development in the pharmaceuticals industry. She is a member of the Clarkson Women’s Rugby Team and AIChE. She enjoys a variety of outdoor activities like fishing, kayaking and camping. After graduating in May 2021, she plans on continuing her studies in graduate school. Welcome to our lab, Brianna!

August 2018: Emma wins Graduate student award from the Eastern Analytical Symposium, Princeton, NJ. Congrats, Emma!

August 2018: Darie Lab attends the Mass Spec Summer School in Madison, WI and present their work

August 2018: Darie Lab attends the Mass Spec Summer School in Madison, WI

July 2018: Cristiana presented her work at the local SURE conference at Clarkson

July 2018: Devika and Cristiana presented their work at the Protein Society Symposium in Boston, MA

July 2018: Emma & Dr. Darie in the library at the University of  Iasi, Romania

July 2018: Emma visits Iasi, Romania to present her work, together with Dr. Darie, at the 2nd intermational summer school in proteomics

June 2018: Dr. Darie visits Iasi, Romania and delivers presentations at the Al. I. Cuza University/Biology Department, Petru Poni Institute of Chemistry, Veterinary School of Medicine University and University of Medicine & Pharmacy

June 2018: Kelly successfully defended her PhD defense. Congrats, Dr. Wormwood!

June 2018: Kelly successfully defended her PhD defense. Congrats, Dr. Wormwood!

June 2018: The Proteomics Lab members (Kelly, Roshi, Devika, Emma, Madhuri, Cristiana & William) in San Diego at the ASMS conference

June 2018: The Proteomics Lab members (Kelly, Roshi, Devika, Emma, Madhuri, Cristiana & William) in San Diego at the ASMS conference

June 2018: Erasmus+ visitors, Profs. Hritcu & Stefan form Al I Cuza University of Iasi, Romania present their work in the Department of Chemsitry & Biomolecular Science

May 2018: Darie Lab members attend the Graduate student symposium at SUNY Buffalo, NY

May 2018: Darie Lab attends the Center for Materials Processing (CAMP) meeting in Finger Lakes and present their work

May 2018: Darie Lab attends the Center for Materials Processing (CAMP) meeting in Finger Lakes

May 2018: Dr. Aslebagh with the lab members

May 2018: Roshi just walked graduation and was hooded. Congratulations, Dr. Aslebagh!

May 2018: Kelly's paper is out

May 2018: Emma will visit Romania as an invited speaker

May 2018: The new Erasmus+ program between Clarkson University & Al. I. Cuza University of Iasi, Romania kicks off

May 2018: William van Doorn from the Netherlands visit our lab

May 2018: Madhuri wins travel award to travel to mass spec summer school. Congrats, Madhuri!

May 2018: Devika won a travel award to present her work at the ASMS. Congrats, Devika!

March 2018: Dr. Mihasan became a Fulbright Ambassador

March 2018: Dr. Daniela Seidler from the University of Hannover Medical School.

March 2018: William Petrus Theodorus Maria van Doorn joins the Biochemistry & Proteomics Lab. Welcome to our lab, William!

March 2018: Madhuri presented her first poster at the ACS Northern New York section conference, held at SUNY Potsdam. She also won her first award:  Best Graduate Poster Presentation Award. Congratulations, Madhuri!

February 2018: Alicia Bushey joins the Biochemistry & Proteomics Lab. Welcome to our Lab, Alicia!

March 2018: Devika won the American Society for Mass Spectrometry (ASMS) Travel Award. Congratulations, Devika!

February 2018: Emma presented her work in the department seminar. Congrats!

February 2018: Roshi successfully defended her PhD exam. Congratulations, Dr. Aslebagh!

January 2018: Kelly presented her work within the department seminar series

January 2018: Kelly will present her work within the department seminar series

January 2018: Cristiana Dumbraveanu joins the Biochemistry & Proteomics Lab as an Erasmus+ exchange student. Welcome to our Lab, Cristiana!

December, 2017: Madhuri Jayathirtha joins the Biochemistry & Proteomics Lab as a graduate student. Welcome to our Lab, Madhuri!

December, 2017: Danielle Whitham joins the Biochemistry & Proteomics Lab. Welcome to our Lab, Danielle!

December, 2017: Desmond Horowitz joins the Biochemistry & Proteomics Lab. Welcome to our Lab, Desmond!

December, 2017: Sydney Stradtman joined the Biochemistry & Proteomics Lab. Welcome to our Lab, Sydney!

December, 2017: German Martinez joined the Biochemistry & Proteomics Lab. Welcome to our Lab, German!

December, 2017: Devika presented her seminar within the department. Congratulations, Devika!

November, 2017: Prof. Alina Zamfir from National Institute of Research in Electrochemistry & Condensed Matter Timisoara, Romania, will present her work at Clarkson in three different seminars; Walsh seminar is one of them

November, 2017: Prof. Zamfir delivered a lecture in the Department of Chemistry & Biomolecular Science

November, 2017: Prof. Zamfir delivered a lecture in the Biochemistry I class

October, 2017: Devika is on the news: she won a travel award that will allow her to attend the 2017 ASMS Fall Workshop on Top-Down Proteomics (November 2-3) in Boston, MA
https://www.clarkson.edu/news/clarkson-university-graduate-students-award-further-research-sleep-apnea-heart-disease

September, 2017: Devika won a travel award that will allow her to attend the 2017 ASMS Fall Workshop on Top-Down Proteomics (November 2-3) in Boston, MA

August, 2017: Roshi won the ASBMB travel award to attend the 12th Symposium on Mass Spectrometry in the Health & Life Sciences (August 20-24, San Francisco, CA). At the conference, she met Dr. Darie’s postdoc Advisor, Dr. Thomas Neubert (New York University School of Medicine).

July 2017: Devika, Emma, Marius & Jacob attended the Protein Society Symposium in Montreal, Canada

July 2017: Dr. Darie attended the European Chemical Biology Symposium in Budapest, Hungary

June 2017: Drs. Darie & Mihasan establish new Erasmus+ exchange program

NEW EXCHANGE

Two professors from Clarkson University and Alexandru Ioan Cuza University of Iasi, Romania, have established an exchange program between the two universities.

https://www.clarkson.edu/news/new-exchange-program-established-romanian-university

June 2017: Kelly, Roshi, Emma, Devika, Jacob & Marius attended the ASMS conference in Indianapolis, IN

June 2017: Kelly, Roshi, Emma, Devika, Jacob & Marius presented their work at the ASMS

June 2017: Prof. Alina Zamfir & her graduate student, Adrian Robu visited the Proteomics Lab at Clarkson University. They also delivered lectures to our lab members

June 2017: After Prof. Zamfir & Adrian presented their work, the lab members took them to dinner

May 2017: Dr. Mihasan presented a seminar within the Biology Department at State University of New York at Potsdam, NY, hosted by Dr.Robert Ewy.

May 2017: Roshi’s presentation to ASBMB meeting in Chicago was a hot topic and it is all over the news (~30,000,000 viewers!). Here are a few examples:

https://www.drugs.com/news/could-breast-milk-tests-replace-mammograms-65303.html

http://health.usnews.com/health-care/articles/2017-04-22/could-breast-milk-tests-replace-mammograms

http://www.hindustantimes.com/fitness/more-than-mammography-your-breastmilk-may-help-detect-your-cancer-risk/story-cy92o6RQW3dNlYAhk5zGOP.html

http://www.health.com/healthday/could-breast-milk-tests-replace-mammograms

May 2017: Devika & Emma received the travel award from The Protein Society. Congrats, both of you!

May 2017: Dr. Mihasan presented a seminar within the Biology Department at State University of New York at Potsdam, NY, hosted by Dr.Robert Ewy.

May 2017: Jessica Roberge was awarded the Academic Achievement Award. Congrats, Jessica!

May 2017: Jacob Lux joins the Biochemistry & Proteomics Lab at Clarkson University as a summer student intern working under Devika's direct supervision. Welcome to our lab, Jacob!

April 2017: Tyler Wilkinson, member of Prof. Melman’s lab attends ASBMB together with Darie Lab members.

April 2017: Kelly, Roshi, Emma, Devika & Marius present their work at the ASBMB.

April 2017: Dr. Mihasan presented a seminar within the Biology Department at Clarkson University, hosted by Dr. Kenneth Wallace.

April 2017: Dr. Mihasan presented a seminar within the Biology Department at the Saint Lawrence University in Canton, NY. He also presented in the Biology Department at Clarkson University

April 2017: Jacob Lux, the member of Dr. Panama's team from the Masonic Labs visited Clarkson University. He will be a Summer student intern working under Devika's direct supervision.

April 2017: Roshi presented her seminar within our department seminar series.

April 2017: Dr. Darie presented a seminar within the Chemistry Department at the State University of New York at Potsdam. Dr. Mihasan also presented a seminar within the Chemistry Department at the State University of New York at Potsdam.

March 2017: Dr. Mihasan presented his work within the School of Arts & Sciences Walsh Seminar Series

March 2017: Dr. Mihasan in in the news (on the Fulbright Commision’s website)

March 2017: Dr. Mihasan presented his work within our department seminar series. He also presented within the Biochemistry & Proteomics Group.

February 2017: Kelly and Emma were recognized in the Daily Courier Observer for attending the ASMS Sanibel conference on Peptidomics in Clearwater beach, FL.

February 2017: Kelly and Emma attended the ASMS conference on peptidomics. See the news: Two Clarkson University Ph.D. Students Attend Conference on Peptidomics.
http://clarkson.edu/news/2017/news-release_2017-02-10-1.html

February 2017: Darie lab welcomes Dr. Marius Mihasan, from Alexandru Ioan Cuza University of Iasi, Romania, a Fulbright Fellow. He will study the Proteomic Analysis of Nicotine-induced Proteins in Arthrobacter Nicotinovorans.Welcome to our lab, Dr. Mihasan!

January 2017: Lynette Smith joined the Biochemistry & Proteomics Lab. Welcome to our lab, Lynette!

January 2017: Our collaborator from Masonic Labs, Dr. Brian Panama delivered a lecture at Clarkson University

January 2017: Roshi, Kelly & Devika end up on the ASBMB email advertisement

January 2017: Kelly & Emma just attended the Sanibel Conference on Peptidomics in Clearwater Beach, Florida. To attend the conference, Kelly was awarded a travel award.

December 2016: End-of-the-year lab meeting

December 2016: Devika just passed the comprehensive exam. Now she is a Ph.D. candidate. Congratulations, Devika!

November 2016: Darie Lab members present their work at the Eastern Analytical Symposium

November 2016: Clarkson University Professor Visits Research Institute in Romania

http://clarkson.edu/news/2016/news-release_2016-12-12-1.html

The Romanian hosts were Prof. Alina Zamfir and her lab members, Adrian Robu & Mirela Sarbu; below: Opera House in Timisoara, the host city

Dr. Darie also went to Iasi, Romania, where he met with his former BS & MS advisor, Prof. Vlad Artenie

September 2016: Prof. Thomas Neubert, Dr. Darie's postdoc advisor will present his work at Clarkson.

September 2016: Dr. Darie presented a seminar at State University of New York at Buffalo. His host was Dr. Troy Wood.

August 2016: Kelly just passed the comprehensive exam and became a PhD candidate. Congratulations, Kelly!

July 2016: Emma just joined the Biochemistry and Proteomics Group as a graduate student. Welcome to our lab, Emma!

June 2016: Kelly and Will meet with Katie (former undergraduate student in our lab, currently graduate student at U.C. Davis) and Izabela (former graduate student in our lab, currently with Janssen Pharmaceuticals, a division of Johnson & Johnson.

June 2016: Will’s travel award is presented at the ASMS conference. He was one of the seven undergraduates that received this award.

June 2016: Kelly (left) and Will (right) meet with Katie, a former lab member (currently at U.C. Davis) and learn line dancing with a Waters representative, at the ASMS Waters hospitality suite.

June 2016: Will presented his work at the ASMS conference in San Antonio, TX (left at the Monday, regular session; right: at the Sunday, undergraduate session)

June 2016: Kelly presented her work at the ASMS conference in San Antonio, TX

May 2016: Drs. Darie (Clarkson University) and Panama (Masonic Labs) enter in a research collaboration on sleep apnea; they also deliver lectures at the 2016 CAMP meeting in Canandaigua, NY

May 2016: Sapan is hooded by his mentors: Dr. Darie & Dr. Clarkson

May 2016: Sapan with Dr. Darie, his academic Ph.D. advisor

May 2016: Proteomics Lab has a record number of graduates! Congratulations, Ashley, Cassia, Emma, Megan, Andre, Tracy & Sapan!

May 2016: Proteomics Lab reaches record number!

May 2016: Prof. Katz’s book in which Roshi contributed with a chapter is published.

May 2016: Roshi was offered an internship with Cytokinetics in San Francisco, CA. Congrats, Roshi!

May 2016: Will, Kelly & Devika in the Daily Courier Observer

May 2016: Clarkson University Chemistry Student Earns Travel Award to Present Research on Proteins

http://clarkson.edu/news/2016/news-release_2016-05-03-2.html

April 2016: Sapan was awarded $2,350 to attend the "Mouse Development, Stem Cells & Cancer" course at Cold SPring Harbor LAboratory. Congrats, Sapan!

April 2016: Xulan presented her Honors poster at the SURE Conference and won an award. Congrats, Xulan!

April 2016: Ashley & Megan presented her Honors thesis at the SURE Conference. Congrats, Ashley & Megan!

April 2016: Roshi, Kelly & Devika attended the Experimental Biology meeting in San Diego, CA. Roshi was also awarded a travel stipend to attend this conference.

April 2016: Sapan successfully defended his PhD thesis. Congratulations, Dr. Patel!

April 2016: Two More Clarkson University Students Awarded Prestigious Goldwater Scholarships

Left to right: Kaitlin Dunn (Goldwater Scholar), Louis DeRidder (honorable mention), and Xulan Deng (Goldwater Scholar).

Two more Clarkson University honors students have been awarded Goldwater Scholarships and one has received an honorable mention. 

Kaitlyn Dunn '17, a physics and electrical engineering double major from Penfield, N.Y., and Xulan Deng '18, a biomolecular science and chemistry double major from New York City, have both been named Goldwater Scholars.

Louis DeRidder '18, a chemical engineering major from Glens Falls, N.Y., received honorable mention.

Including this year’s scholars, 33 Clarkson University students have received this highly coveted award since the scholarships were first awarded in 1989. This is the 17th consecutive year that at least one Clarkson student has received a Goldwater Scholarship.

The Goldwater Scholarship is the most prestigious award in the United States given to undergraduates studying in mathematics, science and engineering. It is given to sophomores and juniors who demonstrate “outstanding potential." There were only 252 scholarships awarded for the 2016-2017 academic year.

Clarkson is one of the top five colleges and universities for the number of Goldwater Scholars in the past five years in New York state and one of only 26 institutions nationwide to win a Goldwater every year since 2005.

Read more here...

Xulan was formerly a member of Professor Mario Wreidt's Lab before joing the Darie Research Group

March 2016: Devika presented her first seminar within our department.

February 2016: Oscar Mario Rodriguez joins the Darie Lab

Oscar Mario Rodriguez obtained his Biology BS and a Minor in Art and Art History from St. Lawrence University in 2014. His work focused on the proficiency and practicality of scientific research methods regarding cell biology, cell cultures, organic chemistry, histology and confocal/SEM microscopy. Oscar worked on the transfection of Green Fluorescent Protein into B12 mammalian cells and tested different combinations of fluorescent/confocal microscopy staining for Xenopus laevis tadpole tissues in order to further study vertebrate metamorphosis. He is a devoted individual to science and the benefits scientific research can provide to others. He began working in Costel Darie's Proteomics lab as a research technician in Spring 2016.

January 2016: Roshi was awarded the American Society for Biochemistry & Molecular Biology (ASBMB) Graduate Travel Award. This award ($1,000) will allow Roshi to attend the ASBMB 2016 annual meeting in April 2016 in San Diego, CA, to present her research. Congratulations, Roshi!

January 2016: Ian joins Darie Lab.

Ian is a freshman from Lyme, New Hampshire currently pursuing a bachelor’s degree in Chemistry with the interest in a double major with molecular biology. He graduated from Thetford Academy in the spring of 2015 and came to Clarkson as a Freshman that fall. He started working in the lab in the Spring of 2016. Ian is interested in studying the biological basis for disease on the molecular and genetic level as well as the potentially beneficial applications for genetically modified organisms in society. Ian is also a member of the Outing Club and the Track Club at Clarkson and enjoys running, hiking, and skiing during his free time. Welcome to our lab, Ian!

January 2016: Darie Lab upgrades the instrumentation: we completed the installation of a new Xevo G2 QTOF mass spectrometer coupled with a NanoAcquity UPLC!

December 2015: André joins the Darie Lab.

André is a senior at Clarkson University, majoring in Chemical Engineering with a minor in Chemistry and concentration in Biomolecular Engineering. He is interested in pharmaceuticals and would like to improve drug delivery methods. He enjoys traveling and spending time with his family in France and Portugal as well as playing golf. Welcome to our lab, André!

December 2015: Roshi was selected as a recipient of the Ada Yonath graduate student travel award (travel at the ASBMS meeting). Congratulations, Roshi!

December 2015: Tracy joins the Darie Lab.

Tracy is a senior chemical engineering major with a concentration in biomolecular engineering and minors in Chemistry, Biomedical Engineering, and Project Management. She was a Research and Development intern at SI Group in Niskayuna, NY. In 2012, she went to Nicaragua on a medical mission and since then, she has had a strong interest in pharmaceuticals and research and development. She hopes to make a difference in the life science industry using her leadership and problem solving skills. Welcome to our lab, Tracy!

December 2015: Roshi passed the comprehensive exam. Congrats, Roshi!

November 2015: Jamie joins the Darie Lab. Welcome to our lab, Jamie!

Jamie N. Schwab
BS, Clarkson University, 2017
Major in Chemical Engineering
Concentration in Biomolecular Engineering
Minors in Chemistry and Biomedical Engineering

 

 

 

 

 

Jamie is a junior majoring in Chemical Engineering with a Concentration in Biomolecular Engineering and Minors in both Chemistry and Biomedical Engineering. She is very interested in Research and Development but she is not sure yet which companies she is most interested in. She really loves both Regeneron Pharmaceuticals and Proctor and Gamble. Jamie is from right outside Buffalo NY. She went to Attica High School and graduated in 2013. She came to Clarkson University in awe of all the amazing opportunities and I am very happy that I did. She am not only interested in courses and clubs that have to do with her major but she is also very involved in clubs and courses that have nothing to do with her academics. She believes it is important to be skilled all around. She took shop classes and she is involved in the Concrete Canoe, and loves new experiences. She also has an on campus job as a First Year Seminar Peer Educator.

 

November 2015: Darie Lab went to the Eastern Analytical Symposium in Somerset, NJ. Roshi & Cassia had poster presentations. Devika, Kelly & Dr. Darie delivered oral presentations.


November 2015: Dr. Darie delivered a lecture at Old Dominion University. Potential collaboration with marine biologists were also discussed.

 

November 2015: Sapan delivered a seminar within our department on quorum sensing in leukemia

November 2015

Clarkson University Researchers Have Young Benefactor

Keillor Dilger (front) with (left to right) Aviva Gold, Costel Darie, Alisa Woods, Kelly Wormwood, Devika Channaveerappa, and Roshanak Aslebagh.

Keillor Dilger has already mastered the art of selling, so fundraising for a cause was her next logical step. That came easily to her as well, but the Potsdam native turned to her mother for help in deciding where to donate the $82.01 she raised for autism.

You see, Keillor is six years old. She opted to present her gift to Clarkson University to support autism research taking place there. That makes her the youngest donor anyone there can recall, but what really impressed the second-grader was the “very cool” tour she took of a research lab on campus.

Read more...

October 2015

Clarkson University Doctoral Students to Present Research on Protein Biomarkers for Cancer, Autism at Conference

Devika Channaveerappa, Costel Darie, Kelly Wormwood

Two Clarkson University chemistry doctoral students have been invited to present at the Eastern Analytical Symposium and Exposition in November.

Devika Channaveerappa of Bangalore, India, and Kelly Wormwood of Lowville, N.Y., will travel to the annual symposium in Somerset, N.J., to deliver oral presentations in the technical session on bioanalysis and biomarker discovery. This is the second year presenting at the Eastern Analytical Symposium and Exposition for both students, who work with Associate Professor of Chemistry & Biomolecular Science Costel Darie.

Channaveerappa will present her project "Proteomics Study to Identify the Protein Differences in Human Breast Milk from Cancer Patients and Controls Using Mass Spectrometry." This project is in collaboration with Professor of Environmental Toxicology Kathleen Arcaro of the University of Massachusetts Amherst. 

Read more...

September 2015

Keillor Dilger, a second grader at Potsdam Lawrence Ave Elementary School, decided to do a fundraiser for autism research and to give what she collected to our lab. Thank you Keillor! Your generous gift will help us to understand autism! In the pictures: left, with Kelly, Roshi & Devika. Right: with her mom, Ms. Aviva Gold and Drs. Woods & Darie. We hope you had fun visiting the lab Keillor and thank you for your generosity, Keillor!

 

September 2015:

Chocolate & Caffeine May Boost Cognitive & Motor Skills, Clarkson University Researchers Say

A chocolate bar might help you negotiate your next business deal, say Clarkson University researchers who are teaming up for a series of studies on the effects of caffeine, cocoa and dark chocolate on cognitive function and fatigue.

Assistant Professor of Physical Therapy & Physician Assistant Studies Ali Boolani is researching the effects of synthetic versus natural caffeine and adaptogens on the mind and body. His research focuses on the effects each has on cognitive function, mood, fine motor task performance, blood pressure and heart rate.

Along with Associate Professor of Chemistry & Biomolecular Science Costel Darie, the researchers will administer a 100 milligram shot of caffeine to participants. Before and after the caffeine dose, they will measure cognitive and motor function as well as levels of cortisol, a hormone released in response to stress and low blood sugar.

Read more...

September 2015:

Clarkson University Chemistry Doctoral Student Wins Scholarship for Single Cell Analysis Research

A Clarkson University chemistry doctoral student won a $1,500 scholarship from Cold Spring Harbor Laboratory to study single cell analysis, this summer.
 
Sapan Patel of Gujarat, India, attended a single cell analysis course this summer at Cold Spring Harbor Laboratory in Cold Spring Harbor, N.Y. Patel works in Clarkson Trustee Dr. Bayard D. Clarkson Sr.'s lab at the Sloan-Kettering Institute.
 
Patel said the experience was an excellent opportunity for him to learn the latest developments, methods and innovations in the field of single cell analysis.
 
Scientists had previously believed cell populations were homogenous, and genomics, trancriptomics or epigenomics measurements at population level were averaged, resulting in a loss of critical information that can only be obtained at the single cell level. Now, Patel said, several studies confirm that cell populations vary at the single cell level and the importance of studying them one cell at a time.
 
Patel said the course allowed him to learn more about technologies to analyze single cells, including transcriptomics, genomics, epigenomics, metabolomics, peptidomics, single cell western blotting, single cell stimulation, transfection and making probes against proteins with molecular evolution methods.
 
Students in the course were also familiarized with upcoming technologies such as soft x-ray technology and how to characterize single cells in their natural microenvironment.
 
"The course included hands-on research as well as several lecturers demonstrating how to utilize different methods to characterize single cells," Patel said. "This course will be really helpful for me to understand some of the questions that we are trying to answer while studying cancer cell-to-cell communication, and it also will be helpful in my future career."
 
Patel thanks his mentors, Bayard D. Clarkson Sr. at Sloan Kettering Institute and Associate Professor of Chemistry & Biomolecular Science Costel Darie at Clarkson University, for their support and advice.
 

Clarkson University launches leaders into the global economy. One in five alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world’s pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and the health professions, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.

August 2015:

Jennifer Boryczka joins Darie Lab. Jenn is a Chemistry and Biomolecular Science major. She is expecting to graduate in 2018 with a bachelor's degree. Welcome to our lab, Jenn!

 

August 2015:
Ashley Boryczka joins Darie Lab. Ashley is a Chemistry and Biomolecular Science major at Clarkson University, Class of 2018. Welcome to our lab, Ashley!

 

August 2015:
Cassia Chapman joins Darie Lab. Cassia is a senior Biology major with a minor in Communication. She participates actively in the community as well as on campus with her involvement in the Golden Knotes and Theta Phi Alpha fraternity. After graduation, Cassia will be attending Graduate school for a concentration in Regenerative Medicine or Bioethics. Welcome to our lab, Cassia!

August 2015:

Willem Duckworth joins Darie Lab. Willem is currently a sophomore at Clarkson University, and is working to earn a BS in Chemistry. He graduated from Nonnewaug High School in Woodbury, CT, in 2014. Welcome to our lab, Will!

 

July 2015:
Dr. Darie Receives tenure & promotion to Associate Professor at Clarkson University. Congrats, Dr. Darie!
http://www.clarkson.edu/news/2015/news-release_2015-08-27-1.html

July 2015:

Kelly Devika & Megan attended the Protein Society Conference in Barcelona, Spain
http://www.barcelocongresos.com.es/protein2015/welcome.html

Kelly & Devika presented their work as a poster presentation,

July 2015:

Emma & Jessica presented their work at SUNY Buffalo Conference. Congrats, both of you!

July 2015:

Emma & Jessica presented their work at the Clarkson SURE Conference. Congrats, both of you!

July 2015:

Kelly attended the 46th Annual Autism Society National Conference in (July 8 – 11) in Denver, CO. Her trip was sponsored by the Darie Lab and the ASPIRE program at Clarkson

June 2015:

Sapan attended a Single Cell Analysis Course-in June 3-16 at Cold Spring Harbor Laboratory and received a $1,500 award. He also attended the Protein Purification course at the Cold Spring Harbor Laboratory and received a $750 award. Congrats, Sapan!

June 2015:

Ashley received the Andrea K. Bridge and John E. O'Beirne Presidential Achievement Scholarship. Congrats, Ashley!

June 2015:

Roshi, Kelly, Devika, Emma & Jess went to ACS NERM Conference in Ithaca, NY. Roshi, Kelly & Devika had oral presentations, while Emma had a poster presentation. This is also Jess’s first attendance to a conference. Congrats, everyone!

June 2015:

Jessica Roberge joins the Darie Lab. Welcome to our lab, Jess!

Jessica Roberge graduated from Souhegan High School in Southern New Hampshire in 2013 and is now a junior at Clarkson University in New York. She is working towards a double major in Biomolecular Science and Chemical Engineering. She also works in the chemistry stockroom during the school year. Jessica started doing research in Dr. Darie's lab in the summer after her sophomore year as a McNair Scholar.

May 2015: Darie Lab went to ASMS Conference in St. Louis MO! Each of them had a poster presentation

May 2015: The Protein Society has awarded Clarkson University chemistry doctoral student Devika Channaveerappa up to $1,500 to travel to the annual symposium and present.

http://clarkson.edu/news/2015/news-release_2015-05-28-1.html

See more at http://www.proteinsociety.org/2015travelawardwinners/

 

May 2015: Drs. Darie & Woods are the 2015 Walker Fellowship winners
http://www.potsdam.edu/newsandevents/52115.cfm

 

May 2015: Farewell, Jonathan!

May 2015: Kelly, Roshi & Devika presented their work as posters at the Graduate Student Symposium in Buffelo. Roshi also had an oral presentation. Congrats, all of you!

May 2015: Matthew & Jonathan just graduated. Farewell, both of you & congrats, class of 2015! Armand also graduated and is officially Dr. Ngounou Wetie. Congrats, Armand!

May 2015: Kelly, Roshi, Devika & Emma’s abstracts were accepted for poster presentations at the NorthEast Regional Meeting in Ithaca, NY. Roshi & Kelly were also accepted for an oral presentation.

May 2015: Kelly’s & Devika’s abstracts were accepted at the Protein Society Conference in July in Barcelona, Spain. Megan will join Kelly & Devika (and will come from her current lab in Konstanz, Germany. Devika was also awarded the Protein Society Travel Award ($1,500). Congrats, all of you! Congrats, Devika!  http://www.proteinsociety.org/meetings/ http://www.barcelocongresos.com.es/protein2015/welcome.html

April 2015: Ashley presented her first poster at SURE conference. Her Honors thesis is co-advised by Profs. Darie, Lufkin & Kraus.

April 2015: Armand’s paper was awarded the Authors’ choice award: A team of researchers at Clarkson University has won the 2015 Journal of Laboratory Automation (JALA) Authors Choice Award for their paper on cancer cells.

Read the article at http://www.slas.org/publications/scientific-journals/2015-slas-journal-achievement-awards/ .

Or see us on TV: http://www.twcnews.com/nys/watertown/news/2015/04/16/clarkson-researchers-given-national-award-for-paper-on-cancer-cells.html

April 2015: Roshi, Devika & Kelly applied for and won a travel award to attend the Graduate Student Symposium organized by University at Buffalo during May 18-20, 2015. All will have a poster presentation. Roshi will also have an oral presentation.  See more at http://www.ubchemgss.org/

April 2015: Kelly presented her first departmental seminar. Congrats, Kelly!

April 2015: Armand successfully defended his PhD thesis. Congratulations, Armand!

March 2015: Megan was accepted to do research in Germany at the University of Konstanz. Congrats, Megan!

March 2015: Roshi, Devika & Kelly presented their work at the Experimental Biology Conference in Boston, MA.

March 2015: Roshi wins the 2015 ASMS Travel Award, to go to the American Society for Mass Spectrometry conference in June 2015 in St. Louis, MO. Congrats, Roshi!

 

March 2015: Darie Lab is even more on the news: Media outlets that have mentioned research on proteomic identification of autism biomarkers and diagnosis (research from Dr. Costel Darie’s lab)

 

Television:

ABC 22, February 3
http://www.mychamplainvalley.com/story/d/story/clarkson-suny-plattsburgh-researchers-saliva-could/30643/Rp7RC5IsdkqwdTU2IA_b_Q

Time Warner Cable, February 14
http://www.twcnews.com/nys/binghamton/news/2015/02/12/saliva-test-could-diagnose-autism-one-day.html

Channel 7 News
http://www.wwnytv.com/news/local/Clarkson-Researchers-Use-Saliva-To-Test-For-Autism-296109851.html

 

Magazines:

Forbes, February 28,
http://www.forbes.com/sites/robertglatter/2015/02/28/proteins-in-saliva-may-help-diagnose-autism/

Clinical Trials News
http://www.clinicaltrialsmagazine.com/test-for-autism-spectrum-disorder/

Youth Health Mag

http://www.youthhealthmag.com/articles/10006/20150218/autism-diagnosis-saliva-autism-spectrum-disorder.htm

 

Newspapers:

North Country Now, February 4
http://northcountrynow.com/news/clarkson-researchers-potsdam-say-saliva-may-help-diagnose-autism-0135825

Allentown Morning Call
http://www.mcall.com/health/mc-study-reports-saliva-may-help-diagnose-autism-20150204-story.html

Watertown Daily Times
http://www.watertowndailytimes.com/article/20150204/NEWS05/150209553

University Herald, February 16
http://www.universityherald.com/articles/15952/20150216/simple-saliva-test-could-diagnose-autism.htm

Autism Daily Newscast
http://www.autismdailynewscast.com/biological-test-autism-may-possible/23424/adn/

 

Websites:

PsychCentral
http://psychcentral.com/news/2015/02/17/saliva-test-may-diagnose-autism/81351.html

News Medical, February 16
http://www.news-medical.net/news/20150217/Saliva-test-holds-promise-to-diagnose-autism-spectrum-disorder-in-children.aspx

BioSpace
http://www.biospace.com/News/saliva-test-to-diagnose-autism-being-developed/364856

Gizmag, February 17
http://www.gizmag.com/saliva-test-diagnosis-autism/36136/

Medscape, February 20
http://www.medscape.com/viewarticle/840087

Genomeweb, February 23
https://www.genomeweb.com/scan/potential-protein-asd-markers

Med Device Online, February 19
http://www.meddeviceonline.com/doc/a-saliva-test-to-diagnose-autism-0001

Babycenter blog, Febaruary 19
http://blogs.babycenter.com/mom_stories/02192015-study-saliva-spit-test-diagnose-autism-kids/

Psychiatry Advisor, February 19
http://www.psychiatryadvisor.com/testing-saliva-could-help-diagnose-autism/article/395402/

Science Daily, February 16
http://www.sciencedaily.com/releases/2015/02/150216125423.htm

Dental tribune, February 23
http://www.dental-tribune.com/mobarticles/content/scope/news/region/americas/id/22203

EpilepsyU.com
http://epilepsyu.com/blog/diagnosing-autism-with-saliva/

 

Radio:

Voice of America
http://www.voanews.com/content/study-says-saliva-test-could-help-diagnose-children-with-autism/2649215.html

 

February 2015: Roshi presents her seminar within the department seminar series. Congrats, Roshi!

 

February 2015: Darie Lab is all over the news:

Clarkson News: http://clarkson.edu/news/2015/news-release_2015-02-02-1.html

Watertown Daily Times: http://www.watertowndailytimes.com/article/20150204/NEWS05/150209553

Daily Courier Observer: http://www.mpcourier.com/article/20150204/DCO/150209483

North Country Now: http://northcountrynow.com/news/clarkson-researchers-potsdam-say-saliva-may-help-diagnose-autism-0135825

Recovery From Autism (RFA): http://www.recoveryfromautism.com/index.php/medicalnewstoday/can-a-saliva-test-diagnose-autism.html

cardinalpointsonline: http://cardinalpointsonline.com/research-offers-potential-earlier-autism-diagnoses/

The Morning Call: http://www.mcall.com/health/mc-study-reports-saliva-may-help-diagnose-autism-20150204-story.html

MNT: http://www.medicalnewstoday.com/releases/288717.php

Also on TV on ABC News: http://www.mychamplainvalley.com/story/d/story/clarkson-suny-plattsburgh-researchers-saliva-could/30643/Rp7RC5IsdkqwdTU2IA_b_Q

February 2015: Armand is awarded the 2015 JALA Authors Choice Award. Congrats, Armand!

January 2015: Armand presented his work at the Department's Seminar Series.


January, 2015: Kelly wins travel award from the The American Society for Biochemistry and Molecular Biology (ASBMB). Kelly will use the funds to attend the ASBMB conference in March in Boston, MA. Congratulations, Kelly!
http://www.clarkson.edu/news/2015/news-release_2015-01-22-1.html

 

January 2015: Xulan, Jonathan & Matthew joined the Biochemistry & Proteomics Lab. Congrats, All of you!

  

December 2014: Roshi, Devika & Kelly present a poster at the Clarkson Graduate Student Symposium (Roshi & Devika presented Kelly's poster). Roshi wins the first place. Congratulations, Roshi, congratulations, all!

 

December 2014: Dr. Darie delivers a seminar in the department of Physics at Clarkson University

November 2014: Dr. Darie delivers a seminar in the department of Chemistry at SUNY Potsdam

November 2014: Dr. Woods delivers lecture at the Science Café in Caanton, NY and Potsdam, NY

November 2014: Adrian & Loredana applied for and were awarded the Ioan Curea Excelence Scholarship (Adrian) and The Faculty Excelence Scholarship (Loredana). Congrats, both of you!

November 2014: Sapan came and successfully presented the seminar on the comprehensive exam. Congratulations, Sapan!

November 2014: Seven posters and an award for Darie Lab at the Eastern Analytical Symposium (EAS). Armand, Kelly, Roshi, Devika (all graduate students) and Emma & Megan (undergraduate students) went and presented their work at the EAS meeting in Somerset NJ. Armand also won one of the four EAS graduate student awards. Congratulations, Armand! Congratulations all presenters!

http://eas.org/
http://easinc.org/wordpress/?page_id=2624


Left picture: Armand at the award ceremony with Dr. Kebbekus, the awards committee chair (left) and Dr. Darie, Armand's advisor (right). Right picture: Armand with Dr. Anne-Francoise Aubry, the 2014 EAS President.

The four graduate and four undergraduate award winners, with the 2014 EAS President, with Dr. Anne-Francoise Aubry

Armand's EAS Graduate Student Award

October, 2014: Sapan successfully presented the seminar in the Department of Chemistry & Biomolecular Science. Sapan is a graduate student in the Darie Lab under Drs. Darie (Clarkson University) and Clarkson (Sloan Kettering Institute). Congratulations, Sapan!


October 2014: Adrian & Loredana present a seminar summary of their work from the past 3 months

October, 2014: Roshi applies for and received the ASMS Travel Award. She will use the award funds to attend the ASMS Fall Workshop Ion Mobility Mass Spectrometry, which will be held at the Seattle Crowne Plaza, Seattle, WA.

http://www.asms.org/conferences/fall-workshop/fall-workshop-homepage

Congrats, Roshi!

 

September, 2014: A new QTOF Ultima API mass spectrometer is successfully installed in our lab. This was possible through Dr. Mary Ann Gawinowicz.
Here are pictures during the installation:

 

After installation:

 

 

 

The first MS and MS/MS spectra (shown is 10 fmol Glufb run through NanoAcquity UPLC coupled with QTOF Ultima API (NanoLC-MS/MS)

 

Undergraduate Students Conducting Summer Research at Clarkson University [From Clarkson University News Release]

http://www.clarkson.edu/news/2014/news-release_2014-08-08-1.html


August, 2014: Emma & Megan won the first place for presenting their poster! Congratulations, Emma & Megan!

 

Emma, Megan, Adrian & Loredana presented their work at the Summer Undergraduate Research Conference at Clarkson University

 

July, 2014: Emma receives a certificate of achievement at the U. Buffalo meeting

 

July, 2014: Emma presents her work at the meeting at U Buffalo

 

July 2014: Meet the Darie Lab members, Summer 2014

Devika
Armand
Kelly
Roshanak
Loredana
Emma
Megan
Adrian

 

July 2014:

Loredana & Adrian, two Romanian graduate students visit Darie Lab.
Loredana Lupu & Adrian Robu, two graduate students from Western University of Timisoara, Romania visit Darie lab. The students, from the Department of Physics applied in Medicine and members of Prof. Alina Zamfir’s Glycoproteomics and Mass Spectrometry Laboratory, came to our lab to gain expertise in proteomics and also teach the members of our lab the insights of glycomics. Welcome to our lab, Loredana & Adrian!

   

June, 2014:

Dr. Alisa Woods delivered an oral presentation to the international meeting in New York City.

http://www.icare4autism.org/events/2014-icare4autism-international-autism-conference/international-autism-conference-speakers/

 

June 2014:

Darie Lab goes to ASMS. The members of the Biochemistry & Proteomics Group went to the International ASMS conference in Baltimore, MD. This was the largest presence of our lab at the ASMS conference: : Katie, Emma Roshi, Devika, Armand, Kelly & Costel. Roshi’s husband (Sadjad), was also present.

 

   

    

 

The lab at the ASMS:

The lab members at the ASMS hospitality suites:

 

 

June, 2014:

Clarkson University Undergraduate Students Recognized for Science Presentations [From Clarkson University News]

Four Clarkson University undergraduate students recently were honored for chemistry and biomolecular science presentations. Read More
http://clarkson.edu/news/2014/news-release_2014-06-18-2.html

 

June, 2014:

Clarkson University Grad Student Wins Award for Autism Study [From Clarkson University News]

Clarkson University graduate student Armand Gatien Ngounou Wetie has won an Eastern Analytical Symposium Graduate Student Research Award for his study of autism spectrum disorders. A Ph.D. student from Cameroon working with Assistant Professor of Chemistry and Biomolecular Science Costel C. Darie and Research Assistant Professor Alisa G. Woods, he is invited to present his research at the symposium and exhibition that takes place from Nov. 17 to 19 at the Garden State Exhibit Center in Somerset, N.J. Read More...

http://www.clarkson.edu/news/2014/news-release_2014-06-11-1.html

May, 2014:

Katie, Kelly, Roshi, Devika & Armand presented their work at the Poster Session of the Chemistry Graduate Student Symposium, organized by the ACS and University at Buffalo. http://www.ubchemgss.com/session-ia

  

  

May, 2014:

Armand delivers an oral presentation at the ACS meeting in Buffalo http://www.ubchemgss.com/session-ia

May, 2014:

Dr. Troy Wood (U. Buffalo) hosts Armand for two weeks for specialized training in mass spectrometry.
http://www.chemistry.buffalo.edu/people/faculty/wood/


Thank you, Dr. Wood!

May, 2014:

Katie, Kelly, Rachel, Bethany, Jarrod, Coleman & Ledwin just graduated. Congratulations & Farewell!

 
 
 

May, 2014:

Katie Beglinger is awarded the ACS Northern New York Award and the Brunauer Award Congratulations, Katie!

 

May 2014:

Clarkson University Researcher to Speak at Autism Conference in NYC [From Clarkson University News]

Clarkson University Research Assistant Professor Alisa G. Woods of the Department of Chemistry and Biomolecular Science will discuss her work at the ICare4Autism International Autism Conference set for June 30-July 2 in New York City.

Woods is one of 29 presenters for the event, which is open to the public and families as well as treatment providers and researchers. Read more...
http://clarkson.edu/news/2014/news-release_2014-05-21-1.html

 

May 2014:

Dr. Urmi Roy presented a poster at the CAMP Annual Technical Meeting, Saratoga Springs, NY.

 

May 2014:

Clarkson University Senior Receives Schwall Fellowship from UC Davis [From Clarkson University News]

Clarkson University senior biomolecular science major Katherine M. Beglinger of Varysburg, N.Y., has received the prestigious Floyd and Mary Schwall Fellowship in Medical Research from the University of California, Davis. Beglinger will attend UC Davis for the Biochemistry, Molecular, Cellular, and Developmental Biology Ph. D. Program. The Schwall Fellowship is offered to a few select graduate applicants who intend to pursue medically-related research. It includes tuition and fees, a research grant, a travel grant and stipend. Read More ...
http://www.clarkson.edu/news/2014/news-release_2014-05-06-2.html

May 2014:

Now available: Advancements of Mass Spectrometry in Biomedical Research (Springer)

http://www.springer.com/chemistry/analytical+chemistry/book/978-3-319-06067-5

April 2014:

Bethany's and Katie's last poster as an official undergraduate at the ACS meeting in Plattsburgh, NY

 

April 2014:

Armand presents a poster about protein modifications at the ACS meeting in Plattsburgh, NY

Kelly presents her first poster as a graduate student at the ACS meeting in Plattsburgh, NY

 

 

April 2014:

Roshi and Devika present their first poster at the ACS meeting in Plattsburgh, NY

 

 

April 2014:

Katie won the best poster award at the ACS NNY meeting, held at SUNY Plattsburgh.
Congratulations, Katie!

 

April 2014:

Rachel received the Marshal Award. Congratulations, Rachel!

 

April, 2014:

Bethany wins the DSean William J. Farrisee Memorial Award.

Congratulations, Bethany!

April, 2014:

Kelly receives the School of Arts & Sciences Award at the Recognition Day The School of Arts & Sciences Award given to an outstanding student-scholar enrolled in a degree program in the School of Arts & Sciences whose studies demonstrate significant interdisciplinary work and excellence in communication. As a student-scholar, the recipient will exemplify the ideal of integration of learning. The recipient of the 2014 School of Arts & Sciences Award is Kelly Wormwood.

Congratulations, Kelly!

 

 

 

April, 2014:

Darie Lab upgrades the Protein Machine! Biochemistry and Proteomics Lab just added another mass spectrometer to their already strong instrumental repertoire! The new instrument, a QTOF Ultima was acquired from Columbia University, thanks to Dr. Mary Ann Gawinowicz, a long standing collaborator of our lab. The new instrument will complement the current QTOF Micro mass spectrometer and the another three TofSpec2E MALDI instruments.

Thank you, Dr. Gawinowicz!

Armand with the newly delivered instrument.

 

How the instrument will look like once we will set it up.

 

April, 2014:

Katie & Emma presented a poster at the SURE Conference, held at Clarkson University. Congratulations, Katie & Emma!

April, 2014:

Dr. Darie presented a seminar at the at the U Connecticut.

April 2014:

Katie goes to UC Davis! Katie will be attending UC Davis for the Biochemistry, Molecular, Cellular, and Developmental Biology Ph. D. Program. On behalf of Graduate Studies and the Biochemistry, Molecular, Cellular and Developmental Biology Graduate Group, Katie was offered the prestigious Floyd and Mary Schwall Fellowship in Medical Research, begining October 1, 2014 through June 30, 2017. This fellowship is offered to a few select graduate applicants who intend to pursue medically-related research. Congratulations, Katie!

March, 2014:

Armand presented his work as an invited speaker at the Department of Chemistry at SUNY Plattsburgh. Congratulations, Armand!

March, 2014:

Emma was accepted in the McNair Program as a McNair student.

Emma was awarded a travel award by the McNair Program Emma will use the award to partially support travel at the international ASMS conference on mass spectrometry and allied topics, which will be held in June, in Baltimore, MD. Congratulations, Emma!

March, 2014:

Kelly & Roshanak (Roshi) won (each of them) the 2014 ASMS Travel Award. They will use the award to partially support theie travel at the intermational ASMS conference on mass spectrometry and allied topics, which will be held in June, in Baltimore, MD. Congratulations, Kelly & Roshi!

March 2014:

Kelly Wormwood is the recipient of the 2014 ASPIRE Graduate Fellowship for study at Clarkson University. This includes a two-year graduate stipend. Congratulations Kelly!

February 2014:

Biochemistry & Proteomics Laboratory entered an agreement on proteomics services with Kendrick Labs. Kendrick Labs, a CRO located in Madison, Wisconsin specialize in sample separation and fractionation for proteomics analysis, with focus on two dimensional electrophoresis (2D-PAGE), one of the most reliable fractionation methods used in proteomics. Biochemistry & Proteomics Laboratory works with Kendrick Labs since November 2013.

Find out more about Kendrick Labs at http://www.kendricklabs.com/index.html

February, 2014 Armand wins the PEGS Student Travel Fellowship!

PEGS, the essential protein engineering summit will gather in Boston’s vibrant seaport district Over 1,600 participants. The value of the fellowship (about $500), will cover part of the travel costs. As a requirement for this fellowship, Armand will also present a poster. Congratulations, Armand!

January 2014: Emmalyn J. Dupree joins the Biochemistry & Proteomics Lab

Emmalyn Dupree graduated from Massena Central School, New York, in 2012. She is now a sophomore at Clarkson University and pursuing a major in Biomolecular Science and a minor in Biology. As work study, she works for the chemistry department in the chemistry stockroom. Emmalyn started research in Dr. Darie’s lab in the spring semester of sophomore year, and plans to continue research during the summer.

Welcome to our lab, Emma!

January 2014: Megan Borland joins the Biochemistry & Proteomics Lab

Megan Borland is a sophomore at Clarkson University, majoring in Biomolecular Science with a minor in Cognitive Neuroscience. She is in the Honors Program and serves on the Honors Council as a student representative. She is also a member of Theta Phi Alpha, a leader for the local Girl Scout Troop, and the secretary of the university’s acapella group, the “Golden Knotes.” She is interested in pursuing a career in research, particularly in pharmaceuticals surrounding conditions such as Autism. Her passion stems from her experiences with her sister with Autism, and her fascination with science and medicine. She enjoys a variety of outdoor activities like skiing, biking and hiking and enjoys volunteering in her community through her school groups and church. She is the founder of a program that collects Christmas gifts for kindergarteners in her local community, which she distributes each December. This spring she is studying abroad in Australia at Griffith University for the semester and will return in the summer to work on research at Clarkson University. After graduating in May 2016 she plans on continuing her studies in graduate school.

Welcome to our lab, Megan!


January 2014: Dr. Alisa Woods has received a $1,000 grant and acceptance to participate in the NIH sponsored 2014 Interdisciplinary Training Conference.

Dr. Alisa Woods has received a $1,000 grant and acceptance to participate in the NIH sponsored 2014 Interdisciplinary Training Conference in Developmental Disabilities being held in Chicago, Illinois on March 4, 2014, followed by the 7th Annual Gatlinburg Conference, one of the premier conferences in the United States for behavioral scientists conducting research in intellectual and related developmental disabilities. http://kc.vanderbilt.edu/gatlinburg/.

January 2014: Devika Channaveerappa joins the Biochemistry & Proteomics Lab.

Devika received her BS and MS in Biotechnology at Bangalore University, Bangalore, India. Her interest of study includes Molecular Biology and Biochemistry. During her MS studies, she did a project on - Detection of ANXA225 Single Nucleotide Polymorphisms in Sickle Cell patients. The project included application of tools like PCR, RFLP and Electrophoresis to detect the presence of SNP in Sickle Cell patients. She has also worked on the Separation of Blue Dextran and protein with Gel Filtration Chromatography and also Purification and Characterization of Parvalbumin protein. While working in these projects, she developed a keen interest in the field of Protein Chemistry and Proteomics.

Welcome to our lab, Devika!

 

January 2014: Ledwin Amaro joins the Biochemistry & Proteomics Lab

Ledwin is currently a chemical engineering senior at Clarkson University. His interest of study includes the pharmaceuticals, biomedical engineering and anything related toward the medical field. Ledwin is currently involved in the Society of Hispanic Professional Engineers at Clarkson. He is set to graduate in May 2014 and continue his interest of study either in graduate school or in a pharmaceutical company. Ledwin’s intermediate goal is to graduate with a degree in chemical engineering and pursuing a job in the pharmaceutical industry and his long term goal is being productive in the pharmaceutical industry doing good and helping people have a better standard of living.

Welcome to our lab, Ledwin!

 

December 2013: Armand G. Ngounou Wetie won the 2013 Graduate Student Award for the best research. Congratulations, Armand!

December 2013: Coleman Larlee and Kelly Wormwood just graduated the Class of December 2013. Congratulations to both of you, Coleman & Kelly!

December 13th: Kelly Wormwood became an undergraduate alumna and a fresh graduate student in the Biochemistry & Proteomics Lab and will work towards her Chemistry PhD degree. Welcome to the lab, again, Kelly!

December, 2013: Rachel A. Skavina, a Chemical Engineer Senior joins the Biochemistry and Proteomics Group

Rachel is currently studying chemical engineering as a senior at Clarkson University, with a concentration in biomolecular engineering and a minor in chemistry. Her special interests include pharmaceuticals, drug discovery, and biotechnology. She holds executive board positions as president of Kappa Delta Chi Sorority Inc. and an officer of Clarkson Univerity Archery Club as well as being an active member of Clarkson University Dance Ensemble, Pep Band, SWE, and AIChE. Rachel plans to graduate in May 2014 and pursue a career in the pharmaceutical industry.

December, 2013: Earl Cash, a Chemical Engineer Junior joins the Biochemistry and Proteomics Group

Earl Cash graduated from Notre Dame Jr./Sr. High School in Utica, New York in 2011. He is currently a junior pursuing a BS in chemical engineering. After recently taking classes pertaining to biology and biochemistry and learning of their applications to chemical engineering, Earl has developed a special interest in biochemical engineering and its applications to pharmaceutical development. Earl's long term goal is to work for a company that specializes in pharmaceuticals and biotechnology.

December, 2013: Ashley Brisbin, a Biology major with a Pre-Physician Assistant concentration, joins the Biochemistry and Proteomics Goups’ lab

Ashley Brisbin is a sophomore at Clarkson University and is pursuing a major in Biology with a concentration of Pre-Physcian Assistant. She is a member of the Clarkson University Honors Program, Tri-Beta Honors Society, Doctors Without Boarders Club, Field Hockey Club, St. Jude's Up Til' Dawn EBoard Team, Delta Zeta Sorority, President of the Pre-Physician Assistant Club, and a volunteer at Canton-Potsdam Hospital. Ashley also enjoys running, spending time with family and friends, and being on the lake during the summer. For the past two summers, Ashley has worked with a disabled child affected by the CMV virus. This past summer, she also took a Licensed Nursing Assistant class, and is planning on working at a local hospital or nursing home this summer. She is also traveling to Guatemala for two weeks this summer to work in rural communities and participate in setting up medical clinics. Ashley plans to graduate in May 2016 and is planning on pursuing a Masters of Science in Physician Assistant Studies.

November, 2013: Mary Williams, a biology major, joins the Biochemistry and Proteomics Goups’ lab
Mary Williams is in her Junior year at Clarkson University and is pursuing a major in Biology. She is a member of Clarkson's Ultimate Frisbee Club as well as the Ski Club. Mary also horseback rides at a barn in St. Regis Falls. For the past two summers, Mary has worked for Heritage Christian Services in her hometown of Webster, NY. This organization services individuals with developmental disabilities. This past summer, she also began working for People Inc. People Inc provides respite workers for families who have members with a developmental disability. Mary plans to graduate in December 2014 and wishes to participate in a medical brigade in Africa. Welcome to the lab, Mary!

October, 2013: Woods honored as recipient of first grant award

Dr. Alisa G. Woods (center) was honored recently at Clarkson University’s Million Dollar Club ceremony for receipt of her grant to study salivary biomarkers in autism spectrum disorder from Shire Pharmaceuticals, LLC. This work is being done with Dr. Costel C. Darie and the laboratory for Biochemistry and Proteomics and Dr. Jeanne Ryan, SUNY Plattsburgh Neuropsychology Clinic and Psychoeducation Services. Also pictured are other recipients of their first grant award.

Congratulations, Alisa!

October 2013: Kelly L. Wormwood Receives First David A. Walsh Fellowship at Clarkson University

Kelly L. Wormwood of Lowville, N.Y., a senior majoring in chemistry and biomolecular science at Clarkson University, has received the David A. Walsh ‘67 Fellowship.

The fellowship, established earlier this year through a donation from Walsh, a resident of Spotsylvania, Va., provided funds for Wormwood’s travel and research supplies during the summer. Read More

September 2013: Bethany M. Wawro joined the Biochemistry & Proteomics Group

Bethany graduated from Skaneateles High School in 2010. She is a senior chemical engineering student, with a minor in Biology and Chemistry, and a concentration on Biomolecular Engineering. She has a special interest in biotechnology and pharmaceuticals and her long term goal is to work for such a company. She is an active member in Alpha Phi Omega, a national coed service fraternity, and Clarkson Union Board, the campus activities programming board.

Welcome to the lab, Bethany!

September, 2013: Armand presented his work within the Department of Chemistry & Biomolecular Science Seminar Series.

September, 2013: Armand successfully defended the comprehensive exam towards his PhD. Congratulation, Armand!

August, 2013: Roshanak Aslebagh joined the Biochemistry and Proteomics Group as a Ph.D. student

Roshanak received her BS in Chemical Engineering at the University of Tehran, Iran and MS in Chemical Engineering- Biomedical Engineering Field at the Tarbiat Modares University (TMU), Tehran, Iran.

During her Bachelor thesis, she worked on the effect of Silica nanoparticles on stability and thermal conductivity of fluids in the lab of Prof. M. Shariati Niasar. During her master studies in Biomedical Engineering, she worked in the field of Nano-biotechnology as her research topic which provoked her enthusiasm toward biotechnology and biomedicine. Her research was in the field of breast cancer cells targeting by means of magnetic nanocarriers. in more details her master thesis was based on the attachment of Anti-HER2 antibody to magnetic Dextran-Spermine coated Iron Oxide nanocarriers for tracking of breast cancer cells in the bioseperation lab of Prof. E. Vasheghani Farahani in TMU, and she did a part of her research in the Hematology lab of Prof. M. Soleimani in Hematology department, Faculty Of Medical Sciences, TMU.

In the Fall of 2013, she joined the Biochemistry and Proteomics Group as a Ph.D. student, where she will combine cell biology, analytical biochemistry, protein chemistry, mass spectrometry and proteomics to investigate Tumor Differentiation Factor and to develop new proteomics approaches for biomarker discovery. Welcome to the lab, Roshanak!

 

August, 2013: Kelly L. Wormwood & Blake Woods presented their work at the Clarkson's Summer SURE conference
Kelly presented her work on identifying serum and saliva biomarkers in Autism Spectrum Disorders at the Summer SURE conference. Blake, a summer high school student presented his work on biochemical investigation of brown and white eggs.

  

August, 2013: Kelly wins the Clarkson's Summer SURE conference. Congratulations, Kelly!

July, 2013: Darie lab thanks donor Bob Matloff, for his generous donation to the autism research program: In Memory of Francis X Stewart.

July, 2013: Clarkson University Chemistry & Biomolecular Science Undergrads Win Awards & Present at Conferences
Three undergraduate students from Clarkson University's Biochemistry & Proteomics Lab, Kelly L. Wormwood '13, Katherine M. Beglinger '14 and Jarrod W. Mattingly '14, led by Chemistry & Biomolecular Science Assistant Professor Costel C. Darie, recently presented their work at the local Spring Undergraduate Research Experience (SURE) conference at Clarkson University and at the regional American Chemical Society Northern New York (ACS NNY) meeting at St. Lawrence University.
More on: http://www.clarkson.edu/news/2013/news-release_2013-07-01-1.html

July, 2013: Drs. Darie and Woods discussed autism biomarkers on the web program, autism brainstorm: http://autismbrainstorm.org/30-new-category/166-dr-alisa-g-woods-neurobiologist-discusses-pinning-down-bio-markers-for-autism. Another webcast will take place on August 8th, 9:00 EST. http://autismbrainstorm.org/35-info-finder-what-s-coming-up/171-monthly-hangout-with-neurobiologist-alisa-g-woods

July, 2013: Blake Woods, an entering High School Jr. from Glen Cove New York joins the lab as a research trainee. Welcome to the lab, Blake!

June, 2013: Coleman Larlee joins Biochemistry & Proteomics lab
Coleman began his scientific career his freshman year at Clarkson University as a Chemical Engineer. Coleman is a member of the Army ROTC program here at Clarkson and is a graduate of the US Army Leadership Development and Assessment Course. Coleman plans to graduate in December of 2013 and pursue a career in the Biopharma industry. Welcome to the lab,Coleman!

June 2013: Dr. Hutanu joins the Biochemistry & Proteomics lab as a visiting scientist
Dr. Hutanu is a life sciences consultant with an industry background ranging from biotechnology to functional coatings industry. Her research interests are in development of novel polymeric coatings and particles as stationary phases for chromatographic separations, coupled with mass spectrometry detection for analysis of nutrients, metabolites, and post-translational modifications on proteins.

June 2013: Drs. Darie and Woods and Kelly Wormwood attended the 2013 Smith-Lemli-Opitz Family and Medical Conference (June 27, 2013 - June 29, 2013), where they collected saliva samples for biomarker analysis. Many thanks to the individuals and families who participated!

  

Clarkson University Research Team Receives $38K Grant for Autism Study
Clarkson University's Laboratory for Biochemistry and Proteomics has received a $38,000 grant to study the potential causes of autism. The laboratory received the grant from Shire Pharmaceuticals LLC. Clarkson researchers will collaborate with cognitive neuroscientist Jeanne Ryan of SUNY Plattsburgh to examine autism indicators in the saliva of children.
More on: http://www.clarkson.edu/news/2013/news-release_2013-06-21-01.html

June 2013: Darie Lab to present to the ASMS conference in Minneapolis, MN
Kelly, Katie, Armand & Dr. Darie presented their work at the American Society for Mass Spectrometry (ASMS) Meeting. ASMS is an annual International Conference on Mass Spectrometry and Allied Topics, attended by more than 6,500 scientists, from approximately 40 countries. More on: http://www.asms.org/

  

June 2013: ASMS conference also organizes hospitality suites, where researchers network and plan foture research projects

June, 2013: ICare4Autism Conference at Albert Einstein College of Medicine Attracts Over 300 People
On June 5, 2013 the International Center for Autism Research and Education (ICare4Autism) held the conference, "Autism: Cutting Edge Research and Promising Treatment Approaches," at Albert Einstein College of Medicine in conjunction with Montefiore Medical Center.
http://www.icare4autism.org/news/2013/06/icare4autism-conference-at-albert-einstein-college-of-medicine-attracts-over-300-people-2/

May 31st, 2013: Izabela Sokolowska successfully defended her Ph.D. Thesis. Congratulations, Dr. Sokolowska!

   

May 31st, 2013: Izabela Sokolowska defends her Ph.D. thesis.
She will be the first graduate student that earned a Ph.D. in the Biochemistry & Proteomics Lab

   

May, 2013: Clarkson University Researcher to Speak at June 5 Autism Conference
Clarkson University Research Assistant Professor Alisa G. Woods of the Department of Chemistry and Biomolecular Science will present at the ICare4Autism International Autism Conference on June 5. http://www.clarkson.edu/news/2013/news-release_2013-05-23-01.html

May 2013: Kelly Wormwood receives a David A. Walsh '67 Undergraduate Summer Research Fellowship
Kelly Wormwood was selected to receive a David A. Walsh '67 Undergraduate Summer Research Fellowship that will allow her to continue to work on her research projects. The fellowship will allow Kelly to pay the room and board expenses, as well as research supplies and travel expenses to scientific conferences. The fellowship is intended to support undergraduate students who major in Chemistry & Biomolecular Science, to initiate and perform research over the Summer and continue it over the next year. Congratulations, Kelly!

May 2013: Dr. Urmi Roy to present a poster at the CAMP conference
Dr. Urmi Roy presented a poster at the CAMP Annual Technical Meeting, Saratoga Springs, NY.

April 2013: Katie Beglinger wins the poster presentation the Chemistry meets Biology conference at St. Lawrence University, meeting sponsored by the ACS NNY section.
Katie Beglionger's poster was selected as the best poster at the ACS NNY poster and won the ACS NNY award. Congratualtions, Katie!

April 2013: Three undergraduate students to present their work at the Chemistry meets Biology Conference, held at St. Lawrence University and sponsored by the American Chemical Society, Northern New York Section (ACS NNY).
Kelly L. Wormwood, Katherine Beglinger, and Jarrod Mattingly, three Biomolecular Science undergraduate students competed for the best undergraduate poster Award at the ACS NNY conference.

  

  

April 2013: Jarrod Mattingly wins the poster presentation the Spring Undergraduate Research Experience (SURE) Conference
Kelly L. Wormwood's poster, presented by Jarrod Mattingly, both Biomolecular Science undergraduate students was selected as the best undergraduate poster and won the 2013 SURE Conference Award. Congratulations, Kelly & Jarrod!

 

April 2013: Three undergraduate students entered the poster competition that will be held by the Spring Undergraduate Research Experience (SURE) Conference
Kelly L. Wormwood, Katherine Beglinger, and Jarrod Mattingly, three Biomolecular Science undergraduate students competed for the best undergraduate poster Award at the SURE conference.

  

January 2013: Two undergraduate students entered the international poster competition that will be held by the American Society for Mass Spectrometry (ASMS).
Kelly L. Wormwood and Katherine Beglinger, two Biomolecular Science undergraduate students will compete for the best undergraduate poster Award at the ASMS 2013 that will be held in Minneapolis, MN. This meeting brings together about 7,000 scientists from all over the world. The undergraduate competition is competitive and limited to a very limited number of posters per year. Both Kelly and Katherine/Katie work together with another undergraduate student Jarrod W. Mattingly, also Biomolecular Science major, work closely with Armand and Izabela, graduate students in Darie lab and also with Drs. Urmi Roy and Alisa G. Woods. Their focus is identification of saliva biomarkers in children with Autism Spectrum Disorder.

December 2012: Izabela Sokolowska wins the Shipley Graduate Student Award
Izabela Sokolowska, a graduate student in the Biochemistry and Proteomics lab led by Dr. Darie won the Shipley Graduate Student Award. The award was announced on the First Annual Chemistry Graduate Student Symposium, held in early December 2012, at Clarkson Universwity The award is given to one graduate student with outstanding achievements in research, service and teaching. Ms. Sokolowska started working towards her PhD on Tumor Differentiation Factor, a new pituitary molecule. She also works on developing new proteomics approaches for biomarker discovery.

November 2012: Armand G. Ngounou Wetie wins ASMS travel Award
Armand attended last year from November 8th to November 9th 2012, the American Society for Mass Spectrometry (ASMS) fall workshop in Boston, Massachusetts. His participation to this workshop was possible thanks to a travel stipend that Armand received from the ASMS. The workshiop is usually limited to 500 participants from all aroud the world. The workshop dealt with mass spectrometry-based analysis of protein phosphorylation and phosphoproteomics in general. Armand got the chance to listen and talk to International renowned speakers in the field of mass spectrometry. Present at the workshop were also many companies from pharmaceutical and biotechnology industry.

May 2012: Izabela Sokolowska accepted to do Summer Internship with Genentech
Izabela Sokolowska, a student in Biochemistry & Proteomics lab, led by Dr. Darie applied to and was accepted to work as an intern over the Summer of 2012 in the Department of Biochemical and Cellular Pharmacology, Genentech Inc. Izabela developed and evaluated purification and mass spectrometry assays for quantification of target proteins in serum in the presence of therapeutic antibody. This is quite a novel direction for Clarkson graduate students.Izabela works toward her PhD since 2009 and is expected to graduate this Summer

 

November 2012: Jarrod Mattingly joins the Biochemistry & Proteomics lab. Jarrod Mattingly is a 2010 graduate from Indian River Central High School in Philadelphia, New York. He also plays baseball for Clarkson University, is the President of Phi Delta Epsilon Pre Medical Fraternity, and color commentates Clarkson Basketball. Jarrod plans to attend medical school in the Fall of 2014 in a joint M.D. and M.B.A. program.

October 2012: Clarkson University's Woods Wins German Psychiatry Prize for Autism Research
[From Clarkson University News]


Dr. Alisa Woods

Clarkson University Research Assistant Professor Alisa Woods of the Department of Chemistry and Biomolecular Science has been awarded the 10th annual Hanse Prize for Psychiatry for her neuropsychiatric research on biomarkers in psychiatry.

Woods was the keynote speaker at the 10th annual Hansesymposium: Mental Health Across the Lifespan -- Molecular Biology and Clinical Presentation of Neuropsychological Development last month at the University of Rostock in Germany. Read more...

August, 2012: Katie Beglinger joins the Biochemistry & Proteomics lab. Katie graduated from Attica High School in 2010 and is majoring in Biomolecular Science and Chemistry. She began her second year as a TA for the Freshman Biology Lab.

August, 2012: Sapan Patel Joins the Biochemistry & Proteomics Laboratory as an external graduate student, under dual mentorship shared by Dr. Costel C. Darie from Clarkson University and Dr. Bayard D. Clarkson from Memorial Sloan Kettering Cancer Center.

Sapan received Master of Science in Biotechnology at the New York University, USA and Bachelor of Pharmacy (Pharmaceutical Sciences) at Saurashtra University, India. During his master study, he worked as research volunteer at Memorial Sloan Kettering Cancer Centre in the lab of Dr. Clarkson. After master study, Sapan joined as a Research Technician at MSKCC in the Dr. Clarkson Lab. My main interest is to study behavior of leukemia at molecular level. Currently, I am working on acute lymphoblastic leukemia and other CML cell lines to study their behavior at different cell densities. Our study shows that the Ph+ ALL3 cells behave differently at different cell densities than other CML cell line. To evaluate the difference in behavior, we are using the traditional thymidine assay with modifications. This study led us to interesting conclusion that the secreted protein collected from exponentially growing high density ALL3 cells can stimulate the low density ALL3 cells to grow without which the low density ALL3 cell will not survive. We are using different chromatographic separation scheme to fractionate the stimulatory protein responsible for proliferation of low density ALL3 cells. Sapan hopes to improve many aspects of cancer biology by identifying the protein molecule with the help of like-minded fellow researches, scientists and physicians. To achieve his long term goal, Sapan joined Dr. Darie group at Clarkson University as an external graduate student to conclude his graduate study. He will obtain the required training to complete my research work from Clarkson University, Columbia University and MSKCC. Sapan hopes to attain such superior goals in this highly collaborative environment at Memorial Sloan-Kettering Cancer Center and Clarkson University.

May, 2012: Clarkson University Researchers Confirm Breast Cancer Regulator Also Found in Prostate Cancer
[From Clarkson University News]

Researchers at Clarkson University in Potsdam, N.Y., led by Chemistry & Biomolecular Science Professor Costel C. Darie, in collaboration with researchers from Columbia University, have now found the binding partner of TDF, a pituitary hormone that had previously been shown to reduce cancer progression in breast cancer cells, in prostate cancer as well.

The study suggests that TDF may play a general role of inhibiting cancerous cells in both the breast and in the prostate. "Finding the receptor for the TDF hormone in both the breast and prostate will allow us to design treatments targeting both cancer types," said Darie. Read more...

Apri, l 2012

Izabela Sokolowska won the 3rd place for the best graduate poster presentation at the Northern New York ACS 3rd Annual Undergraduate and Graduate Chemistry and Biology Research Symposium, Potsdam, NY.

Armand G. Ngounou Wetie won the first place for the best graduate poster presentation at the Northern New York ACS 3rd Annual Undergraduate and Graduate Chemistry and Biology Research Symposium, Potsdam, NY. The prize was shared between two Armand form the Biochemistry and Proteomics Lab and Reshica Baral, the graduate student from the Developmental Biology lab run by Dr. Keenneth Wallace.

January 2012: Clarkson University Researchers Identify Possible Receptor for Key Breast Cancer Regulator
[From Clarkson University News]

A key protein potentially involved in regulating breast cancer progression has been identified by researchers at Clarkson University. Led by Chemistry & Biomolecular Science Professor Costel C. Darie, the team worked to identify the binding partner of Tumor Differentiating Factor (TDF), a pituitary hormone that had previously been shown to reduce cancer progression in breast cancer cells. Read more...

New Release, ASBMB

News Release, North Country Now

News Release, a2z news

News Release, Eurekalert

News Release, FolksHealth

 

January 2012: Clarkson University Scientist Awarded $10,000 Grant From Keep A Breast Foundation to Study New Hormone [From Clarkson University News]

The Keep A Breast Foundation has awarded a $10,000 research grant to Clarkson University Chemistry & Biomolecular Science Professor Costel C. Darie to study a newly identified hormone and to contribute to the prevention and treatment of breast cancer. Read more...

2011 KAB Research Grant Winners

 

June 2011: Clarkson University and SUNY Plattsburgh Scientists Awarded Army DURIP Grant to Purchase Research Instrument. [From Clarkson University News]

 

Two Clarkson University professors and a SUNY Plattsburgh professor have received $107,000 in funding from the Army Research Office Defense University Research Instrumentation Program to advance proteomics research at the two schools.

Proteomics is the large-scale study of proteins, particularly their structures and functions.

Clarkson University Assistant Professor of Chemistry & Biomolecular Science Costel C. Darie (cos-TELL dah-ree-AY) and Associate Professor of Chemistry & Biomolecular Science E. Silvana Andreescu (sil-VAH-na ahn-dray-ESS-cue), and SUNY Plattsburgh Professor and Chair of Chemistry Linda A. Luck will purchase an ultra-nano HPLC with the grant. HPLC stands for high-performance liquid chromatography. This device will be about 500-1000 times more sensitive than the current HPLC at Clarkson.

The instrument separates mixtures of very small compounds through chromatography. When coupled with a mass spectrometer, it provides information about the size, sequence or structure of the compounds.

An instrument used at top research universities, its purchase will allow greater advances in biological and biomedical studies in the region. It will be the first machine of its type in the North Country.

The instrument will be available to users from the of chemistry, biomolecular science and biology departments at Clarkson University and SUNY Plattsburgh, and surrounding colleges and universities, like SUNY Potsdam, SUNY Canton and St. Lawrence University.

The grant program is designed to fill a critical need of scholars by purchasing state-of-the-art equipment that augments current university capabilities or develops new capabilities to perform cutting edge defense research. Read more about Clarkson's Biochemistry and Proteomics Laboratory at http://people.clarkson.edu/~cdarie, and about the BioSem Laboratory at http://web2.clarkson.edu/programs/biosem/index.html. Read about the SUNY Plattsburgh Chemistry and Biochemistry Laboratory at http://www.plattsburgh.edu/academics/chemistry/faculty/luck.php.

News Release from Watertown Daily Times

News Release from North Country Now

News Release from GenomeWeb Daily News

News Release from NNY Gazette

News Release from Press-Republican

News Release from Suny Plattsburgh

News Release from Clarkson University

 

June, 2011: SUNY Plattsburgh Honors Undergraduate Awarded $3,000 for Collaborative Research at Clarkson University Proteomics Lab [From Clarkson University News]

SUNY Plattsburgh pre-medical student Stefanie Russell is working on a project this summer with Clarkson University chemistry & biomolecular science professors Costel Darie and Alisa Woods, and SUNY Plattsburgh Psychology Professor Jeanne Ryan.

Russell was awarded $3,000 from the Redcay endowment for her research proposal "Correlation of Apolipoprotein A1 Levels with Measures of Social Impairment."

Working with children who have autistic spectrum disorder, Russell will compare psychological behavioral measurements of social impairment to measurements of protein in saliva. In doing so, her work will merge the fields of psychology and biochemistry.

The Redcay Research Apprenticeship Award is designed to foster productive student/faculty collaboration in scholarly endeavors. A beloved teacher, dean and president at SUNY Plattsburgh, Edward Redcay set up a major endowment fund to promote and recognize undergraduate student academic excellence in the behavioral sciences and in the honors program.

News Release from Clarkson University

News Release from SUNY Plattsburgh

 

Aprol 2011: Clarkson University Lab First to Beta Test State-of-the-art Fluorescent Microscope [From Clarkson University News]

A Clarkson University laboratory is one of the first to beta test the Etaluma LumaScope, a new state-of-the art fluorescence microscope.

Etaluma of Carlsbad, Calif., has provided the microscope without cost to the Biochemistry and Proteomics Laboratory of Assistant Professor of Chemistry & Biomolecular Science Costel Darie, which will soon begin to implement it.

Darie's lab studies the role of tumor differentiation factor (TDF), a new pituitary hormone, in breast and prostate cells under both physiological (pregnancy and development) and pathological (cancer) conditions.

The lab also studies serum biomarkers in men and women with various types of cancer and in children with autistic spectrum disorders.

The lab will use the microscope for fluorescent immunocytochemistry, to aid in the identification of oncological and neurobiological protein biomarkers and their targets. The LumaScope will be available to users from the departments of Chemistry & Biomolecular Science and Biology.

Etaluma Inc. is a privately held life sciences company focused on bringing analytical and diagnostic instrumentation to a greater spectrum of users by decreasing the cost and complexity of these devices and encouraging the open-source development of applications for their use.

Read more about the Biochemistry and Proteomics Laboratory at http://people.clarkson.edu/~cdarie . Read about the Etaluma LumaScope at http://www.etaluma.com/products/lumascope .

News Release from Clarkson University

News Release from North Country Now

News Release from Watertown Daily Times

 

March 2011: Clarkson University Sophomore Awarded Summer Fellowship at World Acclaimed Sloan-Kettering Cancer Research Center [ From Clarkson University News]

Clarkson University sophomore Martin W. LaFleur of Potsdam, N.Y., has been selected to participate in the Summer Undergraduate Research Fellowship program at the Gerstner Sloan-Kettering Graduate School of Biomedical Sciences at Memorial Sloan-Kettering Cancer Center in New York City.

LaFleur, a biomolecular science and biology double major, is one of only 24 students from around the nation chosen for this intensive, ten-week program.

LaFleur’s career goal is to become an oncology researcher. “This provides the perfect environment and opportunity for me to take a large step toward my goal of someday doing cancer research as a career,” he says.

As part of the fellowship program, he will have an opportunity to work alongside a prominent cancer researcher and obtain hands-on experience in cutting-edge biomedical research. Specific focuses for the fellowship participants include cell-cell interactions, drug development, and tumor immunology.

LaFleur already has extensive lab experience at Clarkson working with Biomolecular Science Professor Costel Darie to find novel prostate cancer biomarkers. He is also currently investigating the effect the tumor differentiation factor protein has on MCF7 breast cancer cells.

He is also a tutor for biology, chemistry, and calculus, and an undergraduate teaching assistant in a general chemistry laboratory.

LaFleur is not the first Clarkson student to participate in the summer cancer research program at the Sloan-Kettering Institute. Adam Searleman ’06 was also awarded this honor as an undergraduate at Clarkson. He is currently enrolled in the M.D./Ph.D. program at Washington University in St. Louis.

Dr. Bayard D. Clarkson Sr., a member of the Clarkson University board of trustees, is an oncologist and hematologist at Sloan-Kettering. He has been researching cancer for more than 50 years.

News Release from Clarkson University

News Release from Watertown Daily Times

 

Kelly Wormwood joins the Protein Chemistry & Proteomics lab. Welcome, Kelly!

Izabela Sokolowska presents her research as both oral and poster presentation at the ACS symposium, held at SUNY Potsdam.

Melissa Butkiewicz presents her research as both oral and poster presentation at the 13th Symposium on Undergraduate Research Experiences (SURE) Conference at Clarkson University. Melissa also presents her research as a poster presentation at the ACS symposium, held at SUNY Potsdam.

Melissa Butkiewicz is the winner for oral presentation at the 13th Symposium on Undergraduate Research Experiences (SURE) Conference at Clarkson University. Congratulations, Melissa!

Rama Yakubu presents his research as both oral and poster presentation at the 13th SURE Conference at Clarkson University. Rama also presents his research as a poster presentation at the ACS symposium, held at SUNY Potsdam.

 

 

Marty LaFleur presents his research as a poster presentation at the 13th SURE Conference at Clarkson University. Marty also presents a poster at the ACS symposium, held at SUNY Potsdam.

November 2010: Jeanette Dorler joined the Biochemistry & Proteomics lab. Jeanette will work on BN-PAGE serum biomarkers. Welcome to our lab, Jeanette! Welcome to the Proteomics World!

November 2010: Jessica Wagner and Ann Marie S. Selva joined the Biochemistry & Proteomics lab.
Jessica and Ann Marie will work initially as volunteers and starting next semester, they will work on a directed study/research. Welcome to our lab, Jessica and Ann Marie! Welcome to the Protein World!

October 2010: Dan Rivera joined the Biochemistry & Proteomics lab. Welcome, Dan!

October 2010: Rama Yakubu receives 2010 Federation of American Societies for Experimental Biology (FASEB)/MinorityAccess to Research Careers (MARC) Travel Award.
The Federation of American Societies for Experimental Biology (FASEB)/MinorityAccess to Research Careers (MARC) Program is pleased to announce selection of Mr. Rama Yakubu for a FASEB MARC Program Poster/Oral Presentation Travel Award. This award will allow Mr. Rama Yakubu to attend the Annual Biomedical Research Conference for Minority Students (ABRCMS) meeting from November 10-13, 2010 in Charlotte, NC. The MARC Program Travel award is a component of a federal grant from the Minority Access to Research Careers Program of the National Institute of General Medical Sciences. The FASEB MARC Program is offering travel awards of up to $1,850 to defray lodging, air, ground transportation, and meeting registration. Congratulations, Rama!

June 2010: Dr. Thomas A. Neubert donated a TofSpec-2E MALDI-TOF mass spectrometer to Dr. Costel C. Darie.
Dr. Thomas A. Neubert, an Associate Professor in the Department of Pharmacology (http://saturn.med.nyu.edu/research/sb/neubertlab/) and Director of the Protein Core Facility (http://saturn.med.nyu.edu/facilities/paf/), Skirball Institute of Biomolecular Medicine, New York University Medical Center donated a mass spectrometer to Dr. Costel C. Darie from Clarkson University. The mass spectrometer is a Micromass TofSpec-2E Matrix Assisted Laser Desorption Ionisation-Time of Flight (MALDI-TOF) instrument with delayed extraction and ion reflector. Dr. Neubert was Dr. Darie's mentor in the field of mass spectrometry of proteins and peptides (proteomics). This instrument is capable to analyze very small amounts (low subpicomole to femtomoles) amounts of compounds, either chemically synthesised or biologically available, with very high accuracy (usually between 50-100 ppm). The range of analysis for this instrument is very large: it can measure small molecular weight compounds (100-5000 Da) in reflectron mode (50 ppm accuracy) and high molecular weight compounds (20-200 kDa) in linear mode (100 ppm accuracy). The instrument is also capable of analyzing compounds in both positive and negative mode, which makes it even more versatile. In his lab, Dr. Darie mainly analyses peptides (small pieces of proteins), either individual ones (for determination of their molecular mass) or in a mixture, for identification of proteins through an approach named peptide mass fingerprinting. Dr. Neubert's lab studies proteins and their roles in cellular signaling events. "While great strides in understanding intracellular signal transduction have been made in recent years by using molecular biological techniques, we feel that a more complete understanding of the dynamics of intracellular decision-making processes can be gained only by studying the proteins directly. We use mass spectrometry as the main tool for our studies because of the wide variety of information about protein structure it can provide while requiring only small amounts of protein for analysis". (http://www.med.nyu.edu/biosketch/neubet01/research). One of Dr. Neubert's lab members, Mr. Steven Blais, helped Dr. Darie to set up the MALDI-TOF MS instrument. In addition, Mr. Jason W.D. Watson, Senior Field Service Engineer and one of the members of technical support from Waters Corporation, US offices (http://www.waters.com/), helped Dr. Darie to troubleshoot and set up the MALDI-TOF MS instrument. Both are still giving Dr. Darie advice and technical advice about the instrument. Thank you, Steven, thank you, Jason, thank you, Tom.

 

June 2010: from the Clarkson Magazine: "When he enrolled in the Clarkson School (TCS) last fall, Marty LaFleur was "almost positive" he would transfer to another university following his year in the special "bridging program" that enables high school students to begin full-time college early. However, once he began taking classes, Marty not only relished the academic challenges, but also thrived in the residential campus environment. And thus, somewhat to his own surprise, he decided to continue at Clarkson University to complete an undergraduate degree in biomolecular science. A straight-A scholar who hopes to pursue a medical career as an oncologist, Marty has already undertaken cancer research alongside faculty as part of the School's summer research program. He typifies the kind of ambitious, talented student traditionally attracted to TCS. But his desire to remain at the University also exemplifies an increasingly evident trend: the proportion of TCS students who choose to stay at Clarkson has expanded from a third to more than half. This phenomenon reflects the University's broadening of academic options, its rising reputation, and the magnetic power of its remarkably supportive, close-knit campus community". Full article at: http://www.clarkson.edu/alumni_magazine/summer2010/clarkson_school.html

May 2010: Christopher Talbot receives the Edward D. Sayer Memorial Award
(Clarkson University 2010 Award from The Department of Chemistry & Biomolecular Science). Congratulations, Chris!

March 2010: Rama Yakubu receives 2010 UNCF-Merck Undergraduate Science Research Scholarship Award.
Rama Yakubu, a junior Biomolecular Science major and member of the Honors Program at Clarkson, has been named a UNCF-Merck Undergraduate Fellow for the 2010-2011 academic year. This prestigious award includes an academic scholarship along with research internships in Merck labs for the 2010 and 2011 summers. Rama has been involved in research his entire time at Clarkson and is currently working with Prof Costel Darie in the Department of Chemistry and Biomolecular Science on a projects involving screening for serum biomarkers. In one project Rama is screening for inflammation detection using novel biochemical and proteomics approaches. In another Rama is monitoring two serum proteins as biomarkers for cell differentiation and cell proliferation in sera from patients with various forms of cancer. Portions of his work will be presented at the North East Regional Meeting of the American Chemical Society in Potsdam, New York, this summer, and at the up-coming meeting of the American Society for Mass Spectrometry in Salt Lake City, Utah. Rama will be finishing his B.S. degree at Clarkson in May 2011. Congratulations, Rama!

January 2010: Christopher Talbot has been accepted in the graduate program in anatomy at Case Western Reserve University.
Congratulations, Chris!

November 2009: Dr. Darie receives a collaborative discount from Waters Corporation.
Dr. Darie receives a collaborative discount from Waters Corporation to purchase a Micromass Quadrupole Time of Flight (QTOF) Micro mass spectrometer (QTOF MS) with a nanospray source. The instrument is capable of analyzing chemical compounds and peptides and to identify their molecular mass. The QTOF-MS is also capable of sequencing peptides that are being analyzed through MS/MS, which involves measuring the mass of the peptide, fragmentation of the peptide and measuring the mass of the peptide fragments. The masses of the peptides analyzed are usually between 800-3000 Da (7-25 amino acids length) with an accuracy of about 10-50 ppm. Detailed information about posttranslational modifications such as phosphorylation or protein truncation may also be analyzed within the same experiment. The QTOF MS instrument is also capable of analyzing large protein molecules (up to 100 kDa) with good accuracy and high reproducibility. In addition, the instrument may be used in both positive and negative modes, allowing the researchers to investigate virtually any type of molecule, regardless of its origins (synthetic or natural compounds).

The instrument has been purchased by Dr. Darie, together with Dr. Artem Melman, Associate Professor in the Department Of Chemistry & Biomolecular Science, Clarkson University. The instrument is being used by the lab members of Dr. Darie for proteomics work and by Dr. Melman for investigation of anti-cancer compounds using chemical synthesis.


The collaborative discount has been made possible through willingness of various people from different academic and industrial settings to help. Therefore, we would like to thank Dr. Cliff Timpson from Roger Williams University (http://faculty.rwu.edu/ctimpson/index.htm) and Mr./Ms./Dr. Michael Balloch, Catalin Doneanu, Tim Mascal, Todd Boyer, David Chamberlin, Scott Nichols, Cathy Bolland, Joanne Boland, Janet Gallager, Laura Mulderig, Nathan Vanderlan, Sean McCarthy & Charles Pragnell from Waters Corporation, US offices (http://www.waters.com/ ) and Keith Compson & Cristian Cojocariu from Waters Corporation, UK offices (http://www.waters.com/. Special thanks are to be addressed to Ms. Laura Mulderig that was able to coordinate the process of collaborative work among all these people and made the purchase and installation of the QTOF MS possible. Thank you, Laura, thank you all! We owe you a good quality spectrum.

 

07 Sep 2009
Darie Appointed Assistant Professor of Biochemistry at Clarkson University [From Clarkson University News]
[A photograph for media use is available at http://www.clarkson.edu/news/photos/darie.jpg ]

Costel C. Darie has been appointed assistant professor of chemistry and biomolecular science at Clarkson University.He began teaching last month.

Darie received his bachelor of science and master of science degrees in biochemistry at Cuza University in Romania, and his Ph.D. in biochemistry from the University of Freiburg in Germany. Darie also received a nursing degree at Vaslui County Hospital, Romania.

Before coming to Clarkson, Darie was a postdoctoral associate at Mount Sinai School of Medicine, a research scientist at the Skirball Institute at New York University and an associate scientist at Mount Sinai.

His research interests include protein-protein interactions, cellular signaling, cancer, serum biomarkers, proteomics and immunotherapy.

Darie has coauthored 17 professional articles and has had a number of abstracts, posters and oral presentations. He is a member of the American Association for the Advancement of Science, the American Chemical Society, the American Society for Mass Spectrometry, the Romanian Society for Mass Spectrometry and the New York Academy of Sciences.

Clarkson University launches leaders into the global economy. One in six alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world's pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and health sciences, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.

http://www.clarkson.edu/news/view.php?id=2307

 

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