Instructor: Ian
Suni Office
Hours: TWTh
236
CAMP
x 4471
Textbook: Bioprocess
Engineering, Basic Concepts, 2nd edition
Michael
L. Shuler and Fikret Kargi
Prentice
Hall, Upper Saddle River, NJ, 2002
Objective: The
objective of this course is to apply principles of cell biology, genetics,
chemistry, biochemistry and chemical engineering to biological processes. The fundamentals of biochemistry, enzyme
kinetics, cell metabolism, genetics and transport phenomena will be covered
first. Then this background knowledge
will be combined with engineering principles to learn about bio-processing. Hopefully the course will cover not only
biochemical reactors, but also other biotechnologies of interest such as
bio-coatings and bio-sensors.
Homework: Homework will be assigned
periodically during the semester. Assignments
will be randomly collected and graded.
Exams: There
will be three hour exams that are tentatively scheduled to be given during
class time on February 17 and April 5 and during final exam week. The third exam will be cumulative.
Grading: Homework: 10%
Laboratory report: 10%
Examinations: 26.67 % each
Course
outline:
Chapter
2: Overview of Biological Basics
Chapter
3: Enzymes
Chapter
4: How Cells Work
Chapter
5: Major Metabolic Pathways
Chapter
6: How Cells Grow
Chapter
7: Stoichiometry
of Microbial Growth
Chapter
8: How Cellular Information is Altered
Chapter
9: Operating Considerations for
Bioreactors for Suspension and Immobilized Cultures
Chapter
10: Selection, Scale-up, Operation
and Control of Bioreactors
Chapter
11: Recovery and Purification of
Products
Homework assignments:
Chapter 2: 2.5, 2.9, 2.12, 2.13, 2.16
Chapter 3: 3.2, 3.4, 3.9, 3.10, 3.13, 3.17, 3.19
Chapter 4: 4.5, 4.7, 4.9, 4.11
Chapter 5: 5.2, 5.5, 5.7, 5.10, 5.11
Chapter 6: 6.1, 6.5, 6.7, 6.9, 6.12, 6.14, 6.16, 6.19
Chapter 7: 7.1, 7.3, 7.5, 7.7
Chapter 9: 9.1, 9.3, 9.5, 9.7, 9.10, 9.11, 9.12
Chapter 10: 10.1, 10.3, 10.5, 10.9, 10.11, 10.13, 10.15