CH465 Biochemical Engineering                                                                                 Spring 2005

 

Instructor:           Ian Suni                                                       Office Hours: TWTh 1-2:40 p.m.

                             236 CAMP                                                            

                             x 4471

                             isuni@clarkson.edu

                                   

Textbook:            Bioprocess Engineering, Basic Concepts, 2nd edition

                             Michael L. Shuler and Fikret Kargi

                             Prentice Hall, Upper Saddle River, NJ, 2002

 

Objective:            The objective of this course is to apply principles of cell biology, genetics, chemistry, biochemistry and chemical engineering to biological processes.  The fundamentals of biochemistry, enzyme kinetics, cell metabolism, genetics and transport phenomena will be covered first.  Then this background knowledge will be combined with engineering principles to learn about bio-processing.  Hopefully the course will cover not only biochemical reactors, but also other biotechnologies of interest such as bio-coatings and bio-sensors.

 

Homework:        Homework will be assigned periodically during the semester.  Assignments will be randomly collected and graded.

 

Exams:               There will be three hour exams that are tentatively scheduled to be given during class time on February 17 and April 5 and during final exam week.  The third exam will be cumulative.

 

Grading:            Homework:               10%

                           Laboratory report:     10%

               Examinations: 26.67 % each

 

Course outline:

 

            Chapter 2: Overview of Biological Basics

            Chapter 3: Enzymes

            Chapter 4: How Cells Work

            Chapter 5: Major Metabolic Pathways

            Chapter 6: How Cells Grow

            Chapter 7: Stoichiometry of Microbial Growth

            Chapter 8: How Cellular Information is Altered

            Chapter 9: Operating Considerations for Bioreactors for Suspension and Immobilized Cultures

            Chapter 10:      Selection, Scale-up, Operation and Control of Bioreactors

            Chapter 11:      Recovery and Purification of Products

 


Homework assignments:

 

Chapter 2:             2.5, 2.9, 2.12, 2.13, 2.16

Chapter 3:             3.2, 3.4, 3.9, 3.10, 3.13, 3.17, 3.19

Chapter 4:             4.5, 4.7, 4.9, 4.11

Chapter 5:             5.2, 5.5, 5.7, 5.10, 5.11

Chapter 6:             6.1, 6.5, 6.7, 6.9, 6.12, 6.14, 6.16, 6.19

Chapter 7:             7.1, 7.3, 7.5, 7.7

Chapter 9:             9.1, 9.3, 9.5, 9.7, 9.10, 9.11, 9.12

Chapter 10:             10.1, 10.3, 10.5, 10.9, 10.11, 10.13, 10.15