Galina Melman

CM 244 Organic Chemistry Laboratory (typical syllabus):

The course is conducted in Fall and Spring semesters for students majoring in Chemistry, Biomolecular Science, Biology, and Chemical Engineering. The course involves several sections run by different instructors and different teaching assistants. I coordinate the laboratory course in Fall and Spring semesters.

CM 241 Organic Chemistry (typical syllabus):

The course teaches about molecular structure of the organic compounds; functional groups involved in basic organic chemistry reactions and classification of reactions; mechanistic part of organic chemistry reactions.

Emphasis is placed on the electronic and structural rationales in each type of reaction.

Each topic studied in the course is accompanied by a homework assignment. Three mid-term exams and cumulative exam at the end of the course assess the leaning outcomes.

CM 242 Organic Chemistry (typical syllabus):

During the second part of the two-semester course we continue to discuss functional groups involved in basic organic chemistry reactions. Particular emphasis is placed on carbonyl functional group. It brings us to the discussion of carbohydrates and peptides. Throughout the second part of the course we will discuss different spectroscopic techniques which are used to characterize of organic compounds with particular emphasis on NMR technique.

The course is accompanied by homework assignments. Three mid-term exams and cumulative exam at the end of the course assess the leaning outcomes.

CM 342 Food Chemistry (syllabus):

This all new course started in Fall 2016 for students majoring in Chemistry, Biomolecular Sciences, Biology, and Chemical Engineering. In this course I integrated the lecture course with experimental course. Course teaches about physical and chemical changes that occur with organic molecules present in food.

PEER REVIEWED JOURNAL PUBLICATIONS

1) E. Katz, J.M. Pingarrón, S. Mailloux, N. Guz, M. Gamella, G. Melman, and A. Melman. "Substance Release Triggered by Biomolecular Signals in Bioelectronic Systems". The Journal of Physical Chemistry Letters 2015, 6(8), pp. 1340–1347.

2) G. Melman, F. Bou-Abdallah, E. Vane, P. Maura, P. Arosio, A. Melman. "Iron release from ferritin by flavin nucleotides". Biochimica Et Biophysica Acta-General Subjects 2013, 1830 (10), pp. 4669-4674.

3) R.P. Narayanan, G. Melman, N.J. Letourneau, N.L. Mendelson, A. Melman. "Photodegradable Iron(III) Cross-Linked Alginate Gels". Biomacromolecules 2012, 13(8), pp. 2465-2471.

4) D. Sun, G. Melman, N.J. LeTourneau, A.M. Hays, A. Melman. "Synthesis and antiproliferating activity of iron chelators of hydroxyamino-1,3,5-triazine family". Bioorganic & Medicinal Chemistry Letters 2010, 20(2), pp. 458-460.

5) G. Melman, P. Vimal, A. Melman. "Complementary Dynamic Assembly around an Iron(III) Cation". Inorganic Chemistry 2009, 48(18), pp. 8662-8664.

6) J. Zhou, G. Melman, M. Pita, M. Ornatska, X.M. Wang, A. Melman, E. Katz. "Biomolecular Oxidative Damage Activated by Enzymatic Logic Systems: Biologically Inspired Approach". Chembiochem 2009, 10(6), pp. 1084-1090.

7) R. Kikkeri, N. Humbert, H. Traboulsi, E. Gumienna-Kontecka, R. Arad-Yellin, G. Melman, M. Elhabiri, A.-M. Albrecht-Gary, and A. Shanzer. "Toward Iron Sensors: Bioinspired Tripods Based on Fluorescent Phenol-oxazoline Coordination Sites". Inorg. Chem. 2007, 46(7), pp 2485 – 2497.

8) Margulies, D.; Felder, C. E.; Melman, G.; Shanzer, A.

"A molecular keypad lock: a photochemical device capable of processing password entries". J. Am. Chem. Soc. 2007; 129(2); pp 347 – 354.

9) Margulies, D.; Melman, G.; Shanzer, A. "A Molecular Full-Adder and Full-Subtractor, an Additional Step toward a Moleculator. J. Am. Chem. Soc. 2006, 128, 4865-4871.

10) Margulies, D.; Melman, G.; Shanzer, A. "Fluorescein as a model molecular calculator with reset capability." Nature Materials 2005, 4, 768-771.

11) Margulies, D.; Melman, G.; Felder, C. E.; Arad-Yellin, R.; Shanzer, A. "Chemical Input Multiplicity Facilitates Arithmetical Processing" J. Am. Chem. Soc. 2004, 126, 15400-15401.